Description
TBDMS-PEG4-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
Product information
CAS Number: 134179-40-1
Molecular Weight: 308.49
Formula: C14H32O5Si
Chemical Name: 2,2,3,3-tetramethyl-4,7,10,13-tetraoxa-3-silapentadecan-15-ol
Smiles: CC(C)(C)[Si](C)(C)OCCOCCOCCOCCO
InChiKey: KZFZMISGZPOLJM-UHFFFAOYSA-N
InChi: InChI=1S/C14H32O5Si/c1-14(2,3)20(4,5)19-13-12-18-11-10-17-9-8-16-7-6-15/h15H,6-13H2,1-5H3
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vitro:
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
Products are for research use only. Not for human use.
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