TBDMS-PEG4-OH


Catalog No. Size PriceQuantity
M32484-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

TBDMS-PEG4-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

Product information

CAS Number: 134179-40-1

Molecular Weight: 308.49

Formula: C14H32O5Si

Chemical Name: 2,2,3,3-tetramethyl-4,7,10,13-tetraoxa-3-silapentadecan-15-ol

Smiles: CC(C)(C)[Si](C)(C)OCCOCCOCCOCCO

InChiKey: KZFZMISGZPOLJM-UHFFFAOYSA-N

InChi: InChI=1S/C14H32O5Si/c1-14(2,3)20(4,5)19-13-12-18-11-10-17-9-8-16-7-6-15/h15H,6-13H2,1-5H3

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Products are for research use only. Not for human use.

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