Description
Amino-Tri-(m-PEG4-ethoxymethyl)-methane is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
Product information
CAS Number: 1428661-67-9
Molecular Weight: 905.08
Formula: C40H80N4O18
Chemical Name: 3-(2-amino-3-{2-[(2,5,8,11-tetraoxatridecan-13-yl)carbamoyl]ethoxy}-2-({2-[(2,5,8,11-tetraoxatridecan-13-yl)carbamoyl]ethoxy}methyl)propoxy)-N-(2,5,8,11-tetraoxatridecan-13-yl)propanamide
Smiles: COCCOCCOCCOCCNC(=O)CCOCC(N)(COCCC(=O)NCCOCCOCCOCCOC)COCCC(=O)NCCOCCOCCOCCOC
InChiKey: HRTAKXVPXIKONP-UHFFFAOYSA-N
InChi: InChI=1S/C40H80N4O18/c1-48-16-19-54-28-31-57-25-22-51-13-7-42-37(45)4-10-60-34-40(41,35-61-11-5-38(46)43-8-14-52-23-26-58-32-29-55-20-17-49-2)36-62-12-6-39(47)44-9-15-53-24-27-59-33-30-56-21-18-50-3/h4-36,41H2,1-3H3,(H,42,45)(H,43,46)(H,44,47)
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vitro:
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
Products are for research use only. Not for human use.
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