N-Benzyl-N-bis-PEG4


Catalog No. Size PriceQuantity
M32493-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

N-Benzyl-N-bis-PEG4 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

Product information

CAS Number: 1680183-01-0

Molecular Weight: 459.57

Formula: C23H41NO8

Chemical Name: 12-benzyl-3,6,9,15,18,21-hexaoxa-12-azatricosane-1,23-diol

Smiles: OCCOCCOCCOCCN(CC1C=CC=CC=1)CCOCCOCCOCCO

InChiKey: OTLYNICMYVWKJD-UHFFFAOYSA-N

InChi: InChI=1S/C23H41NO8/c25-8-12-29-16-20-31-18-14-27-10-6-24(22-23-4-2-1-3-5-23)7-11-28-15-19-32-21-17-30-13-9-26/h1-5,25-26H,6-22H2

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Products are for research use only. Not for human use.

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