Carboxyrhodamine 110-PEG4-alkyne


Catalog No. Size PriceQuantity
M32517-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

Carboxyrhodamine 110-PEG4-alkyne is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

Product information

CAS Number: 2055103-66-5

Molecular Weight: 587.62

Formula: C32H33N3O8

Chemical Name: 2-(6-amino-3-imino-3H-xanthen-9-yl)-5-[(3,6,9,12-tetraoxapentadec-14-yn-1-yl)carbamoyl]benzoic acid

Smiles: C#CCOCCOCCOCCOCCNC(=O)C1=CC(C(O)=O)=C(C=C1)C1C2=CC=C(N)C=C2OC2=CC(=N)C=CC2=1

InChiKey: JXQJIYQBZLRJHC-UHFFFAOYSA-N

InChi: InChI=1S/C32H33N3O8/c1-2-10-39-12-14-41-16-17-42-15-13-40-11-9-35-31(36)21-3-6-24(27(18-21)32(37)38)30-25-7-4-22(33)19-28(25)43-29-20-23(34)5-8-26(29)30/h1,3-8,18-20,33H,9-17,34H2,(H,35,36)(H,37,38)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Products are for research use only. Not for human use.

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