N-Mal-N-bis(PEG2-acid)


Catalog No. Size PriceQuantity
M32521-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

N-Mal-N-bis(PEG2-acid) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

Product information

CAS Number: 2110449-02-8

Molecular Weight: 488.49

Formula: C21H32N2O11

Chemical Name: 3-{2-[2-(N-{2-[2-(2-carboxyethoxy)ethoxy]ethyl}-3-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)propanamido)ethoxy]ethoxy}propanoic acid

Smiles: OC(=O)CCOCCOCCN(CCOCCOCCC(O)=O)C(=O)CCN1C(=O)C=CC1=O

InChiKey: IEXQAPPGJQEYIT-UHFFFAOYSA-N

InChi: InChI=1S/C21H32N2O11/c24-17(3-6-23-18(25)1-2-19(23)26)22(7-11-33-15-13-31-9-4-20(27)28)8-12-34-16-14-32-10-5-21(29)30/h1-2H,3-16H2,(H,27,28)(H,29,30)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Products are for research use only. Not for human use.

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