endo-BCN-PEG2-C2-NHS ester


Catalog No. Size PriceQuantity
M32527-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

endo-BCN-PEG2-C2-NHS ester is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.

Product information

CAS Number: 2243565-12-8

Molecular Weight: 450.48

Formula: C22H30N2O8

Chemical Name: 2,5-dioxopyrrolidin-1-yl 3-[2-(2-{[({bicyclo[6.1.0]non-4-yn-9-yl}methoxy)carbonyl]amino}ethoxy)ethoxy]propanoate

Smiles: O=C(NCCOCCOCCC(=O)ON1C(=O)CCC1=O)OCC1C2CCC#CCCC21

InChiKey: HVVMKCPRACMDSI-UHFFFAOYSA-N

InChi: InChI=1S/C22H30N2O8/c25-19-7-8-20(26)24(19)32-21(27)9-11-29-13-14-30-12-10-23-22(28)31-15-18-16-5-3-1-2-4-6-17(16)18/h16-18H,3-15H2,(H,23,28)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Products are for research use only. Not for human use.

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