Biotin-PEG4-Picolyl azide


Catalog No. Size PriceQuantity
M32553-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

Biotin-PEG4-Picolyl azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

Product information

CAS Number: 2222687-71-8

Molecular Weight: 623.74

Formula: C27H43N8O7S

Chemical Name: 1-({5-[1-(5-{2-oxo-hexahydro-1H-thieno[3,4-d]imidazol-4-yl}pentanamido)-3,6,9,12-tetraoxapentadecan-15-amido]pyridin-2-yl}methyl)triaza-1,2-dien-2-ium

Smiles: N=[N+]=NCC1=CC=C(C=N1)NC(=O)CCOCCOCCOCCOCCNC(=O)CCCCC1SCC2NC(=O)NC12

InChiKey: CELOISJOTXQCGT-UHFFFAOYSA-O

InChi: InChI=1S/C27H42N8O7S/c28-35-31-18-20-5-6-21(17-30-20)32-25(37)7-9-39-11-13-41-15-16-42-14-12-40-10-8-29-24(36)4-2-1-3-23-26-22(19-43-23)33-27(38)34-26/h5-6,17,22-23,26,28H,1-4,7-16,18-19H2,(H3-,29,32,33,34,36,37,38)/p+1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Products are for research use only. Not for human use.

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