m-PEG8-succinimidyl carbonate


Catalog No. Size PriceQuantity
M32558-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

m-PEG8-succinimidyl carbonate is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

Product information

CAS Number: 1372860-04-2

Molecular Weight: 525.54

Formula: C22H39NO13

Chemical Name: 2,5-dioxopyrrolidin-1-yl 2,5,8,11,14,17,20,23-octaoxapentacosan-25-yl carbonate

Smiles: COCCOCCOCCOCCOCCOCCOCCOCCOC(=O)ON1C(=O)CCC1=O

InChiKey: KGBOFEYHJAHPNI-UHFFFAOYSA-N

InChi: InChI=1S/C22H39NO13/c1-27-4-5-28-6-7-29-8-9-30-10-11-31-12-13-32-14-15-33-16-17-34-18-19-35-22(26)36-23-20(24)2-3-21(23)25/h2-19H2,1H3

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Products are for research use only. Not for human use.

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