Description
MS-PEG4-THP is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
Product information
CAS Number: 145927-73-7
Molecular Weight: 356.43
Formula: C14H28O8S
Chemical Name: 2-(2-{2-[2-(oxan-2-yloxy)ethoxy]ethoxy}ethoxy)ethyl methanesulfonate
Smiles: CS(=O)(=O)OCCOCCOCCOCCOC1CCCCO1
InChiKey: IHVHEXYPQZJGKH-UHFFFAOYSA-N
InChi: InChI=1S/C14H28O8S/c1-23(15,16)22-13-11-19-9-7-17-6-8-18-10-12-21-14-4-2-3-5-20-14/h14H,2-13H2,1H3
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vitro:
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
Products are for research use only. Not for human use.
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