N-(Azido-PEG3)-NH-PEG3-acid


Catalog No. Size PriceQuantity
M32573-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

N-(Azido-PEG3)-NH-PEG3-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

Product information

CAS Number: 2183440-72-2

Molecular Weight: 422.47

Formula: C17H34N4O8

Chemical Name: 1-azido-3,6,9,15,18,21-hexaoxa-12-azatetracosan-24-oic acid

Smiles: [N-]=[N+]=NCCOCCOCCOCCNCCOCCOCCOCCC(O)=O

InChiKey: CDPBBXHRNSHWQA-UHFFFAOYSA-N

InChi: InChI=1S/C17H34N4O8/c18-21-20-4-8-27-12-16-29-15-11-26-7-3-19-2-6-25-10-14-28-13-9-24-5-1-17(22)23/h19H,1-16H2,(H,22,23)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Products are for research use only. Not for human use.

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