m-PEG4-amino-Mal


Catalog No. Size PriceQuantity
M32574-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

m-PEG4-amino-Mal is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

Product information

CAS Number: 1263044-81-0

Molecular Weight: 358.39

Formula: C16H26N2O7

Chemical Name: 3-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)-N-(2,5,8,11-tetraoxatridecan-13-yl)propanamide

Smiles: COCCOCCOCCOCCNC(=O)CCN1C(=O)C=CC1=O

InChiKey: DOHTYEHHGXSUJO-UHFFFAOYSA-N

InChi: InChI=1S/C16H26N2O7/c1-22-8-9-24-12-13-25-11-10-23-7-5-17-14(19)4-6-18-15(20)2-3-16(18)21/h2-3H,4-13H2,1H3,(H,17,19)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Products are for research use only. Not for human use.

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