m-PEG5-phosphonic acid ethyl ester


Catalog No. Size PriceQuantity
M32600-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

m-PEG5-phosphonic acid ethyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

Product information

CAS Number: 1807512-42-0

Molecular Weight: 372.39

Formula: C15H33O8P

Chemical Name: diethyl (2,5,8,11,14-pentaoxahexadecan-16-yl)phosphonate

Smiles: COCCOCCOCCOCCOCCP(=O)(OCC)OCC

InChiKey: COMONJQWUBCUJE-UHFFFAOYSA-N

InChi: InChI=1S/C15H33O8P/c1-4-22-24(16,23-5-2)15-14-21-13-12-20-11-10-19-9-8-18-7-6-17-3/h4-15H2,1-3H3

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Products are for research use only. Not for human use.

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