1, 1, 1-Trifluoroethyl-PEG4-aminooxy


Catalog No. Size PriceQuantity
M32621-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

1,1,1-Trifluoroethyl-PEG4-aminooxy is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

Product information

CAS Number: 1895922-78-7

Molecular Weight: 291.26

Formula: C10H20F3NO5

Chemical Name: O-(14,14,14-trifluoro-3,6,9,12-tetraoxatetradecan-1-yl)hydroxylamine

Smiles: NOCCOCCOCCOCCOCC(F)(F)F

InChiKey: PQVCKGCTWRTZFK-UHFFFAOYSA-N

InChi: InChI=1S/C10H20F3NO5/c11-10(12,13)9-18-6-5-16-2-1-15-3-4-17-7-8-19-14/h1-9,14H2

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Products are for research use only. Not for human use.

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