Foscarnet sodium


Catalog No. Size PriceQuantity
M32622-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

Foscarnet sodium (Trisodium phosphonoformate) is a viral DNA polymerase activity inhibitor, leading to reversible suppression of viral replication. Foscarnet sodium is an antiherpesvirus agent used in cytomegalovirus retinitis.

Product information

CAS Number: 63585-09-1

Molecular Weight: 191.95

Formula: CNa3O5P

Chemical Name: trisodium phosphonatoformate

Smiles: [Na+].[Na+].[Na+].[O-]C(=O)P([O-])([O-])=O

InChiKey: DFHAXXVZCFXGOQ-UHFFFAOYSA-K

InChi: InChI=1S/CH3O5P.3Na/c2-1(3)7(4,5)6;;;/h(H,2,3)(H2,4,5,6);;;/q;3*+1/p-3

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: H2O : 60 mg/mL (312.58 mM; Need ultrasonic).

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

Foscarnet sodium (Trisodium phosphonoformate) inhibits Influenza A Victoria (IC50=29 μM), Influenza B HK (IC50=61 μM), and Avian myeloblastosis virus (IC50=5-8 μM),HSV-1, several strains (IC50=0.4-3.5 μM).

Products are for research use only. Not for human use.

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