N-Boc-N-bis(PEG3-NHS ester)


Catalog No. Size PriceQuantity
M32629-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

N-Boc-N-bis(PEG3-NHS ester) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

Product information

CAS Number: 2055042-31-2

Molecular Weight: 719.73

Formula: C31H49N3O16

Chemical Name: 2,5-dioxopyrrolidin-1-yl 3-{2-[2-(2-{17-[(2,5-dioxopyrrolidin-1-yl)oxy]-2,2-dimethyl-4,17-dioxo-3,8,11,14-tetraoxa-5-azaheptadecan-5-yl}ethoxy)ethoxy]ethoxy}propanoate

Smiles: CC(C)(C)OC(=O)N(CCOCCOCCOCCC(=O)ON1C(=O)CCC1=O)CCOCCOCCOCCC(=O)ON1C(=O)CCC1=O

InChiKey: PQSUBGGFVYSVNA-UHFFFAOYSA-N

InChi: InChI=1S/C31H49N3O16/c1-31(2,3)48-30(41)32(10-14-44-18-22-46-20-16-42-12-8-28(39)49-33-24(35)4-5-25(33)36)11-15-45-19-23-47-21-17-43-13-9-29(40)50-34-26(37)6-7-27(34)38/h4-23H2,1-3H3

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Products are for research use only. Not for human use.

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