Antitumor agent-23


Catalog No. Size PriceQuantity
M32642-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

Antitumor agent-23 is a potent anti-cancer agent with GI50s of 38, 48, 5, 27, 80, and 28 nM for lymphoma cell line GRANTA-519, KARPAS-422, KARPAS-299, RAMOS, DAUDI, and RAJI, respectively. Antitumoral activity.

Product information

CAS Number: 2355185-12-3

Molecular Weight: 506.72

Formula: C28H50N4O4

Chemical Name: (3S)-1-[(2S)-4-methyl-1-[(8S)-8-methyl-3-[(pyrrolidin-1-yl)methyl]-1,5-dioxa-9-azaspiro[5.5]undecan-9-yl]-1-oxopentan-2-yl]-3-(2-methylpropyl)piperazin-2-one

Smiles: C[C@H]1CC2(CCN1C(=O)[C@H](CC(C)C)N1CCN[C@@H](CC(C)C)C1=O)OCC(CN1CCCC1)CO2

InChiKey: WQHBHIAUTXCQFP-WNWGCBLOSA-N

InChi: InChI=1S/C28H50N4O4/c1-20(2)14-24-26(33)32(13-9-29-24)25(15-21(3)4)27(34)31-12-8-28(16-22(31)5)35-18-23(19-36-28)17-30-10-6-7-11-30/h20-25,29H,6-19H2,1-5H3/t22-,23?,24-,25-,28?/m0/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

Antitumor agent-23 (0.001-100 μM; 5 days) inhibits lymphoma cells proliferation. Antitumor agent-23 (2-70 nM; 72 hours) induces p53 protein expression and p53 lysine 382 acetylation (K382Ac-p53) in HPV-positive cervical cancer cell.

Products are for research use only. Not for human use.

Payment & Security

PayPal Venmo

Your payment information is processed securely. We do not store credit card details nor have access to your credit card information.

You may also like

Recently viewed