Fluorescein-PEG5-NHS ester


Catalog No. Size PriceQuantity
M32673-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

Fluorescein-PEG5-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

Product information

CAS Number: 2353409-62-6

Molecular Weight: 795.81

Formula: C38H41N3O14S

Chemical Name: 2,5-dioxopyrrolidin-1-yl 1-[({3',6'-dihydroxy-3-oxo-3H-spiro[2-benzofuran-1,9'-xanthen]-5-yl}carbamothioyl)amino]-3,6,9,12,15-pentaoxaoctadecan-18-oate

Smiles: OC1=CC2OC3=CC(O)=CC=C3C3(OC(=O)C4=CC(=CC=C34)NC(=S)NCCOCCOCCOCCOCCOCCC(=O)ON3C(=O)CCC3=O)C=2C=C1

InChiKey: SBHQUOCPGORZNI-UHFFFAOYSA-N

InChi: InChI=1S/C38H41N3O14S/c42-25-2-5-29-31(22-25)53-32-23-26(43)3-6-30(32)38(29)28-4-1-24(21-27(28)36(47)54-38)40-37(56)39-10-12-49-14-16-51-18-20-52-19-17-50-15-13-48-11-9-35(46)55-41-33(44)7-8-34(41)45/h1-6,21-23,42-43H,7-20H2,(H2,39,40,56)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Products are for research use only. Not for human use.

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