Fmoc-NMe-PEG4-NHS ester


Catalog No. Size PriceQuantity
M32675-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

Fmoc-NMe-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

Product information

CAS Number: 2228857-30-3

Molecular Weight: 598.64

Formula: C31H38N2O10

Chemical Name: 2,5-dioxopyrrolidin-1-yl 1-({[(9H-fluoren-9-yl)methoxy]carbonyl}(methyl)amino)-3,6,9,12-tetraoxapentadecan-15-oate

Smiles: CN(CCOCCOCCOCCOCCC(=O)ON1C(=O)CCC1=O)C(=O)OCC1C2=CC=CC=C2C2=CC=CC=C21

InChiKey: GDTKRPKAACWJRV-UHFFFAOYSA-N

InChi: InChI=1S/C31H38N2O10/c1-32(31(37)42-22-27-25-8-4-2-6-23(25)24-7-3-5-9-26(24)27)13-15-39-17-19-41-21-20-40-18-16-38-14-12-30(36)43-33-28(34)10-11-29(33)35/h2-9,27H,10-22H2,1H3

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Products are for research use only. Not for human use.

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