DiOC6(3) iodide - CAS# 53213-82-4


Catalog No. Size PriceQuantity
M32676-C Contact sales@xcessbio.com for quotation $100

Description

DiOC6(3) iodide, CAS No. 53213-82-4, Synonyms 3, 3'-Dihexyloxacarbocyanine iodide, is a carbocyanine dye which can be used to monitor changes in mitochondrial membrane potential.

Product information

CAS Number: 53213-82-4

Molecular Weight: 572.52

Formula: C29H37IN2O2

Synonym:

3, 3'-Dihexyloxacarbocyanine iodide

Chemical Name: 3-hexyl-2-[(1E)-3-[(2Z)-3-hexyl-2,3-dihydro-1,3-benzoxazol-2-ylidene]prop-1-en-1-yl]-1,3-benzoxazol-3-ium iodide

Smiles: [I-].CCCCCC[N+]1C2=CC=CC=C2OC=1/C=C/C=C1\OC2=CC=CC=C2N\1CCCCCC

InChiKey: XVLXYDXJEKLXHN-UHFFFAOYSA-M

InChi: InChI=1S/C29H37N2O2.HI/c1-3-5-7-13-22-30-24-16-9-11-18-26(24)32-28(30)20-15-21-29-31(23-14-8-6-4-2)25-17-10-12-19-27(25)33-29;/h9-12,15-21H,3-8,13-14,22-23H2,1-2H3;1H/q+1;/p-1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO : 50 mg/mL (87.33 mM; Need ultrasonic).

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

Addition of cells to the cuvette containing 0.25 μM 3,3'-Dihexyloxacarbocyanine iodide (DiOCg(3)) leads to an increase in fluorescence, equilibration is rapid and is complete by 4 min. When f-met-leu-phe (10-7 M) is added to neutrophils preequilibrated with 3,3'-Dihexyloxacarbocyanine iodide, there is a short lag period of 5 seconds. The lag period is followed by a rapid loss of fluorescence. Examination of 3,3'-Dihexyloxacarbocyanine iodide loaded neutrophils using fluorescence microscopy demonstrates that in resting neutrophils the brightest fluorescence is associated with long thin organelles which corresponds to the distribution of mitochondria.

Products are for research use only. Not for human use.

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