Description
m-PEG6-Ms is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
Product information
CAS Number: 130955-39-4
Molecular Weight: 374.45
Formula: C14H30O9S
Chemical Name: 2,5,8,11,14,17-hexaoxanonadecan-19-yl methanesulfonate
Smiles: COCCOCCOCCOCCOCCOCCOS(C)(=O)=O
InChiKey: UPZJIJLNUYSFIH-UHFFFAOYSA-N
InChi: InChI=1S/C14H30O9S/c1-17-3-4-18-5-6-19-7-8-20-9-10-21-11-12-22-13-14-23-24(2,15)16/h3-14H2,1-2H3
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vitro:
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
Products are for research use only. Not for human use.
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