Description
Propargyl-O-C1-amido-PEG3-C2-NHS ester is a non-cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
Product information
CAS Number: 2101206-78-2
Molecular Weight: 414.41
Formula: C18H26N2O9
Chemical Name: 2,5-dioxopyrrolidin-1-yl 3-[2-(2-{2-[2-(prop-2-yn-1-yloxy)acetamido]ethoxy}ethoxy)ethoxy]propanoate
Smiles: C#CCOCC(=O)NCCOCCOCCOCCC(=O)ON1C(=O)CCC1=O
InChiKey: ODGFZGOFEXLWHL-UHFFFAOYSA-N
InChi: InChI=1S/C18H26N2O9/c1-2-7-28-14-15(21)19-6-9-26-11-13-27-12-10-25-8-5-18(24)29-20-16(22)3-4-17(20)23/h1H,3-14H2,(H,19,21)
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vitro:
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
Products are for research use only. Not for human use.
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