Description
Mal-PEG2-oxyamine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
Product information
CAS Number: 1146245-73-9
Molecular Weight: 244.24
Formula: C10H16N2O5
Chemical Name: 1-(2-{2-[2-(aminooxy)ethoxy]ethoxy}ethyl)-2,5-dihydro-1H-pyrrole-2,5-dione
Smiles: NOCCOCCOCCN1C(=O)C=CC1=O
InChiKey: KJLHERZPDIQDDV-UHFFFAOYSA-N
InChi: InChI=1S/C10H16N2O5/c11-17-8-7-16-6-5-15-4-3-12-9(13)1-2-10(12)14/h1-2H,3-8,11H2
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vitro:
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
Products are for research use only. Not for human use.
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