Mal-NH2 TFA


Catalog No. Size PriceQuantity
M32731-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

Mal-NH2 (TFA) is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs.

Product information

CAS Number: 146474-00-2

Molecular Weight: 254.16

Formula: C8H9F3N2O4

Chemical Name: 1-(2-aminoethyl)-2,5-dihydro-1H-pyrrole-2,5-dione; trifluoroacetic acid

Smiles: NCCN1C(=O)C=CC1=O.OC(=O)C(F)(F)F

InChiKey: YNHKVOGCDPODMT-UHFFFAOYSA-N

InChi: InChI=1S/C6H8N2O2.C2HF3O2/c7-3-4-8-5(9)1-2-6(8)10;3-2(4,5)1(6)7/h1-2H,3-4,7H2;(H,6,7)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Products are for research use only. Not for human use.

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