Description
NO2-SPP-sulfo is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
Product information
CAS Number: 663598-66-1
Molecular Weight: 465.48
Formula: C14H15N3O9S3
Chemical Name: 1-({4-[(5-nitropyridin-2-yl)disulfanyl]pentanoyl}oxy)-2,5-dioxopyrrolidine-3-sulfonic acid
Smiles: CC(CCC(=O)ON1C(=O)C(CC1=O)S(O)(=O)=O)SSC1=CC=C(C=N1)[N+]([O-])=O
InChiKey: YIZUQMMWCFGOAA-UHFFFAOYSA-N
InChi: InChI=1S/C14H15N3O9S3/c1-8(27-28-11-4-3-9(7-15-11)17(21)22)2-5-13(19)26-16-12(18)6-10(14(16)20)29(23,24)25/h3-4,7-8,10H,2,5-6H2,1H3,(H,23,24,25)
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vitro:
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
Products are for research use only. Not for human use.
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