Fmoc-Val-Ala-PAB-PNP - CAS# 1394238-92-6


Catalog No. Size PriceQuantity
M32743-50 50 mg, in stock $66
M32743-250 250 mg, in stock $196
M32743-500 500 mg, in stock $352
M32743-1S 1g, in stock $550
M32743-C Contact sales@xcessbio.com for quotation $100

Description

Fmoc-Val-Ala-PAB-PNP is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

Product information

CAS Number: 1394238-92-6

Molecular Weight: 680.70

Formula: C37H36N4O9

Synonym:

Fmoc-Val-Ala-PABC-PNP

Chemical Name: {4-[(2S)-2-[(2S)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-3-methylbutanamido]propanamido]phenyl}methyl 4-nitrophenyl carbonate

Smiles: CC(C)[C@H](NC(=O)OCC1C2=CC=CC=C2C2=CC=CC=C21)C(=O)N[C@@H](C)C(=O)NC1C=CC(COC(=O)OC2C=CC(=CC=2)[N+]([O-])=O)=CC=1

InChiKey: ZJHZWBDLYYJQAV-WYOOIXGGSA-N

InChi: InChI=1S/C37H36N4O9/c1-22(2)33(40-36(44)48-21-32-30-10-6-4-8-28(30)29-9-5-7-11-31(29)32)35(43)38-23(3)34(42)39-25-14-12-24(13-15-25)20-49-37(45)50-27-18-16-26(17-19-27)41(46)47/h4-19,22-23,32-33H,20-21H2,1-3H3,(H,38,43)(H,39,42)(H,40,44)/t23-,33-/m0/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

Products are for research use only. Not for human use.

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