Mal-NH-PEG6-CH2CH2COOPFP ester


Catalog No. Size PriceQuantity
M32746-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

Mal-NH-PEG6-CH2CH2COOPFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

Product information

CAS Number: 1599432-34-4

Molecular Weight: 670.58

Formula: C28H35F5N2O11

Chemical Name: 2,3,4,5,6-pentafluorophenyl 1-[3-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)propanamido]-3,6,9,12,15,18-hexaoxahenicosan-21-oate

Smiles: O=C(CCOCCOCCOCCOCCOCCOCCNC(=O)CCN1C(=O)C=CC1=O)OC1C(F)=C(F)C(F)=C(F)C=1F

InChiKey: PELJIWMJFINXNE-UHFFFAOYSA-N

InChi: InChI=1S/C28H35F5N2O11/c29-23-24(30)26(32)28(27(33)25(23)31)46-22(39)4-7-40-9-11-42-13-15-44-17-18-45-16-14-43-12-10-41-8-5-34-19(36)3-6-35-20(37)1-2-21(35)38/h1-2H,3-18H2,(H,34,36)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Products are for research use only. Not for human use.

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