Description
NO2-SPDMV is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
Product information
CAS Number: 663598-98-9
Molecular Weight: 399.44
Formula: C15H17N3O6S2
Chemical Name: 2,5-dioxopyrrolidin-1-yl 4-methyl-4-[(5-nitropyridin-2-yl)disulfanyl]pentanoate
Smiles: CC(C)(CCC(=O)ON1C(=O)CCC1=O)SSC1=CC=C(C=N1)[N+]([O-])=O
InChiKey: AQKHEWNNTCBJPY-UHFFFAOYSA-N
InChi: InChI=1S/C15H17N3O6S2/c1-15(2,26-25-11-4-3-10(9-16-11)18(22)23)8-7-14(21)24-17-12(19)5-6-13(17)20/h3-4,9H,5-8H2,1-2H3
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vitro:
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
Products are for research use only. Not for human use.
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