Omaciclovir


Catalog No. Size PriceQuantity
M32780-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

Omaciclovir (H2G) is a potent and selective inhibitor of herpesvirus replication. Omaciclovir is a nucleoside analog with antiviral activity.

Product information

CAS Number: 124265-89-0

Molecular Weight: 253.26

Formula: C10H15N5O3

Chemical Name: 2-amino-9-[(2R)-4-hydroxy-2-(hydroxymethyl)butyl]-6,9-dihydro-1H-purin-6-one

Smiles: NC1NC(=O)C2N=CN(C[C@@H](CCO)CO)C=2N=1

InChiKey: SCBFBAWJWLXVHS-ZCFIWIBFSA-N

InChi: InChI=1S/C10H15N5O3/c11-10-13-8-7(9(18)14-10)12-5-15(8)3-6(4-17)1-2-16/h5-6,16-17H,1-4H2,(H3,11,13,14,18)/t6-/m1/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO : 230 mg/mL (908.16 mM; Need ultrasonic).

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

Omaciclovir is a nucleoside analog with in vitro inhibitory activity against varicella-zoster virus (VZV), herpes simplex virus types 1 and 2 (HSV-1 and -2), Epstein-Barr virus, and human herpesvirus 6. Omaciclovir is also efficacious in simian varicella virus-infected monkeys. Omaciclovir shows antiviral activities against different human herpesviruses with EC50s of 0.72 ± 0.1, 0.62 ± 0.2, 0.015 ± 0.004, 0.048 ± 0.023, 0.047 ± 0.004, 0.035 ± 0.022, and 0.016 ± 0.003 μM for MRC-5 VZV-32, MRC-5 Molly, MeWo VZV-32, MeWo Molly, MeWo Emily, MeWo VZ11, and MeWo VZ30, respectively.

Products are for research use only. Not for human use.

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