Description
NO2-SPDB-sulfo is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
Product information
CAS Number: 663598-89-8
Molecular Weight: 451.45
Formula: C13H13N3O9S3
Chemical Name: 1-({4-[(5-nitropyridin-2-yl)disulfanyl]butanoyl}oxy)-2,5-dioxopyrrolidine-3-sulfonic acid
Smiles: [O-][N+](=O)C1=CN=C(C=C1)SSCCCC(=O)ON1C(=O)C(CC1=O)S(O)(=O)=O
InChiKey: AJTQYMNCOAZOGJ-UHFFFAOYSA-N
InChi: InChI=1S/C13H13N3O9S3/c17-11-6-9(28(22,23)24)13(19)15(11)25-12(18)2-1-5-26-27-10-4-3-8(7-14-10)16(20)21/h3-4,7,9H,1-2,5-6H2,(H,22,23,24)
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vitro:
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
Products are for research use only. Not for human use.
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