Mal-Sulfo-DBCO


Catalog No. Size PriceQuantity
M32790-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

Mal-Sulfo-DBCO is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

Product information

CAS Number: 2028281-86-7

Molecular Weight: 578.59

Formula: C28H26N4O8S

Chemical Name: 1-[(3-{2-azatricyclo[10.4.0.0⁴,⁹]hexadeca-1(16),4,6,8,12,14-hexaen-10-yn-2-yl}-3-oxopropyl)carbamoyl]-2-[3-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)propanamido]ethane-1-sulfonic acid

Smiles: OS(=O)(=O)C(CNC(=O)CCN1C(=O)C=CC1=O)C(=O)NCCC(=O)N1CC2=CC=CC=C2C#CC2=CC=CC=C12

InChiKey: IQQMMWCHYXQNOT-UHFFFAOYSA-N

InChi: InChI=1S/C28H26N4O8S/c33-24(14-16-31-25(34)11-12-26(31)35)30-17-23(41(38,39)40)28(37)29-15-13-27(36)32-18-21-7-2-1-5-19(21)9-10-20-6-3-4-8-22(20)32/h1-8,11-12,23H,13-18H2,(H,29,37)(H,30,33)(H,38,39,40)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

Products are for research use only. Not for human use.

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