Description
Fmoc-Phe-Lys(Trt)-PAB is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
Product information
CAS Number: 1116085-98-3
Molecular Weight: 863.05
Formula: C56H54N4O5
Chemical Name: (9H-fluoren-9-yl)methyl N-[(1S)-1-{[(1S)-1-carbamoyl-5-[(triphenylmethyl)amino]pentyl][4-(hydroxymethyl)phenyl]carbamoyl}-2-phenylethyl]carbamate
Smiles: NC(=O)[C@H](CCCCNC(C1C=CC=CC=1)(C1C=CC=CC=1)C1C=CC=CC=1)N(C1C=CC(CO)=CC=1)C(=O)[C@H](CC1C=CC=CC=1)NC(=O)OCC1C2=CC=CC=C2C2=CC=CC=C21
InChiKey: YYQHCELGLDFYGB-XWQGWOARSA-N
InChi: InChI=1S/C56H54N4O5/c57-53(62)52(31-17-18-36-58-56(42-21-7-2-8-22-42,43-23-9-3-10-24-43)44-25-11-4-12-26-44)60(45-34-32-41(38-61)33-35-45)54(63)51(37-40-19-5-1-6-20-40)59-55(64)65-39-50-48-29-15-13-27-46(48)47-28-14-16-30-49(47)50/h1-16,19-30,32-35,50-52,58,61H,17-18,31,36-39H2,(H2,57,62)(H,59,64)/t51-,52-/m0/s1
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vitro:
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
Products are for research use only. Not for human use.
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