Description
Sulfo-DMAC-SPP is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
Product information
CAS Number: 663599-11-9
Molecular Weight: 491.56
Formula: C17H21N3O8S3
Chemical Name: 1-[(4-{[3-(dimethylcarbamoyl)pyridin-4-yl]disulfanyl}pentanoyl)oxy]-2,5-dioxopyrrolidine-3-sulfonic acid
Smiles: CN(C)C(=O)C1=CN=CC=C1SSC(C)CCC(=O)ON1C(=O)C(CC1=O)S(O)(=O)=O
InChiKey: BZNFRACCQKDBEB-UHFFFAOYSA-N
InChi: InChI=1S/C17H21N3O8S3/c1-10(29-30-12-6-7-18-9-11(12)16(23)19(2)3)4-5-15(22)28-20-14(21)8-13(17(20)24)31(25,26)27/h6-7,9-10,13H,4-5,8H2,1-3H3,(H,25,26,27)
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vitro:
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
Products are for research use only. Not for human use.
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