DSHS00884


Catalog No. Size PriceQuantity
M32829-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

DSHS00884 is a potent human papillomavirus E6 inhibitor with an IC50 of 10 μM.

Product information

CAS Number: 675104-49-1

Molecular Weight: 308.38

Formula: C12H12N4O2S2

Chemical Name: 3-{[(2-nitrophenyl)sulfanyl]methyl}-4-(prop-2-en-1-yl)-4,5-dihydro-1H-1,2,4-triazole-5-thione

Smiles: C=CCN1C(=S)NN=C1CSC1=CC=CC=C1[N+]([O-])=O

InChiKey: VWFIHGWHMXSTAO-UHFFFAOYSA-N

InChi: InChI=1S/C12H12N4O2S2/c1-2-7-15-11(13-14-12(15)19)8-20-10-6-4-3-5-9(10)16(17)18/h2-6H,1,7-8H2,(H,14,19)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO : 250 mg/mL (810.69 mM; Need ultrasonic).

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

DSHS00884 stabilizes p53 levels in HPV-positive cells by blocking E6-mediated p53 degradation with an IC50 of 2.5-25 μM.

Products are for research use only. Not for human use.

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