Description
T.cruzi-IN-1 is a potent Trypanosoma cruzi inhibitor with an IC50 of 8 nM. T.cruzi-IN-1, a 4-trifluoromethyl substituted analog, has the potential for both the acute and chronic stages of Chagas disease.
Product information
CAS Number: 1350920-22-7
Molecular Weight: 390.44
Formula: C22H25F3N2O
Chemical Name: N-benzyl-N-methyl-1-{[4-(trifluoromethyl)phenyl]methyl}piperidine-3-carboxamide
Smiles: CN(CC1C=CC=CC=1)C(=O)C1CN(CC2C=CC(=CC=2)C(F)(F)F)CCC1
InChiKey: UYYRGUHHPKHWTR-UHFFFAOYSA-N
InChi: InChI=1S/C22H25F3N2O/c1-26(14-17-6-3-2-4-7-17)21(28)19-8-5-13-27(16-19)15-18-9-11-20(12-10-18)22(23,24)25/h2-4,6-7,9-12,19H,5,8,13-16H2,1H3
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Solubility: DMSO : 50 mg/mL (128.06 mM; ultrasonic and warming and heat to 60°C).
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vitro:
T.cruzi-IN-1 inhibits Trypanosoma cruzi replication and has an IC50 of 61.6 μM for toxicity.
Products are for research use only. Not for human use.
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