Description
MAT2A inhibitor 1 is a methionine adenosyltransferase 2A (MATA2) inhibitor with an IC50 less than l00 nM.
Product information
CAS Number: 2201057-10-3
Molecular Weight: 526.61
Formula: C31H22N6OS
Chemical Name: 6-(2-methyl-1,3-benzothiazol-6-yl)-2,3-diphenyl-5-[(pyridin-2-yl)amino]-4H,7H-pyrazolo[1,5-a]pyrimidin-7-one
Smiles: CC1=NC2=CC=C(C=C2S1)C1C(=O)N2N=C(C(=C2NC=1NC1=CC=CC=N1)C1C=CC=CC=1)C1C=CC=CC=1
InChiKey: ZTNQNZDNHUAVEI-UHFFFAOYSA-N
InChi: InChI=1S/C31H22N6OS/c1-19-33-23-16-15-22(18-24(23)39-19)27-29(34-25-14-8-9-17-32-25)35-30-26(20-10-4-2-5-11-20)28(36-37(30)31(27)38)21-12-6-3-7-13-21/h2-18,35H,1H3,(H,32,34)
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Solubility: DMSO : 5 mg/mL (9.49 mM; Need ultrasonic and warming).
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vitro:
MAT2A inhibitor 1 (Compound 196) is a safe and effective compound that prevents and manages cancers while reducing or avoiding the toxicities and/or side effects associated with the conventional therapies. The cancers include those that are refractory to standard treatments, such as surgery, radiation therapy, chemotherapy and hormonal therapy.
Products are for research use only. Not for human use.
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