RXFP3/4 agonist 1


Catalog No. Size PriceQuantity
M32863-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

RXFP3/4 agonist 1 is an agonist of relaxin family peptide 3/4 receptor (RXFP3/4), with EC50s of 82/2 nM, respectivley. RXFP3/4 agonist 1 increases food intake in rats.

Product information

CAS Number: 2351104-40-8

Molecular Weight: 383.87

Formula: C20H22ClN5O

Chemical Name: N''-[2-(4-chlorophenyl)ethyl]-N-[(E)-[(7-ethyl-5-hydroxy-1H-indol-3-yl)methylidene]amino]guanidine

Smiles: CCC1=CC(O)=CC2=C1NC=C2/C=N/NC(N)=NCCC1C=CC(Cl)=CC=1

InChiKey: NQWXHRRWWPCDAJ-BRJLIKDPSA-N

InChi: InChI=1S/C20H22ClN5O/c1-2-14-9-17(27)10-18-15(11-24-19(14)18)12-25-26-20(22)23-8-7-13-3-5-16(21)6-4-13/h3-6,9-12,24,27H,2,7-8H2,1H3,(H3,22,23,26)/b25-12+

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

RXFP3/4 agonist 1 (Compound 4) inhibits orskolin-stimulated cAMP accumulation in CHO-K1 cells stably overexpressing RXFP3 and RXFP4, with EC50s of 12.8 and 1.6 nM, respectively.

Products are for research use only. Not for human use.

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