Methuosis inducer 1


Catalog No. Size PriceQuantity
M32865-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

Methuosis inducer 1 is a potent methuosis inducer. Anticancer activity.

Product information

CAS Number: 2240205-30-3

Molecular Weight: 487.48

Formula: C27H20F3N5O

Chemical Name: N-(4-methyl-3-{[6-(pyridin-3-yl)-1H-pyrrolo[2,3-b]pyridin-4-yl]amino}phenyl)-3-(trifluoromethyl)benzamide

Smiles: CC1=CC=C(C=C1NC1C=C(N=C2NC=CC=12)C1=CN=CC=C1)NC(=O)C1=CC(=CC=C1)C(F)(F)F

InChiKey: MNEWQRRQMLENPL-UHFFFAOYSA-N

InChi: InChI=1S/C27H20F3N5O/c1-16-7-8-20(33-26(36)17-4-2-6-19(12-17)27(28,29)30)13-22(16)34-24-14-23(18-5-3-10-31-15-18)35-25-21(24)9-11-32-25/h2-15H,1H3,(H,33,36)(H2,32,34,35)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO : 41.67 mg/mL (85.48 mM; Need ultrasonic).

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

Methuosis inducer 1 (Compound 13) shows a broad spectrum of cytotoxicity against a panel of human cancer cell lines with IC50 values of 0.326±0.026 μM, 1.370±0.061 μM, 1.662±0.128 μM, 1.892±0.092 μM, 1.571±0.066 μM, 2.268±0.100 μM, 2.611±0.739 μM, 1.008±0.042 μM, 1.566±0.015 μM, and 1.197±0.344 μM for A375, SK-MEL-28, SK-MEL-30, A549, MDA-MB-231, MDA-MB-435S, MCF-7, HCT116, BGC823, HepG2 cells, respectively.

Products are for research use only. Not for human use.

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