JF585, SE


Catalog No. Size PriceQuantity
M32922-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

JF585, SE (JF585, NHS) is an orange fluorescent dye containing an NHS ester that can be conjugated with primary amine groups. JF585, SE can be used immediately for structured illumination (SIM) and stimulated emission depletion (STED) imaging and could be converted to photoactivatable derivative for single-molecule localization microscopy (SMLM) experiments.

Product information

CAS Number: 1811539-88-4

Molecular Weight: 649.59

Formula: C34H27F4N3O6

Chemical Name: 1-[10-(2-carboxylato-5-{[(2,5-dioxopyrrolidin-1-yl)oxy]carbonyl}phenyl)-7-(3,3-difluoroazetidin-1-yl)-9,9-dimethyl-2,9-dihydroanthracen-2-ylidene]-3,3-difluoro-1λ⁵-azetidin-1-ylium

Smiles: CC1(C)C2=CC(C=CC2=C(C2=CC=C(C=C12)N1CC(F)(F)C1)C1=CC(=CC=C1C([O-])=O)C(=O)ON1C(=O)CCC1=O)=[N+]1CC(F)(F)C1

InChiKey: GFNMIANIZWSVQR-UHFFFAOYSA-N

InChi: InChI=1S/C34H27F4N3O6/c1-32(2)25-12-19(39-14-33(35,36)15-39)4-7-22(25)29(23-8-5-20(13-26(23)32)40-16-34(37,38)17-40)24-11-18(3-6-21(24)30(44)45)31(46)47-41-27(42)9-10-28(41)43/h3-8,11-13H,9-10,14-17H2,1-2H3

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

Maximum absorption wavelength (λabs)=585 nm, maximum emission wavelength (λem)=609 nm. The JF585-SNAP-tag ligand (24) also functioned as a cellular label. The new HaloTag ligands derived from JF585 and JF635 show a high degree of chromogenicity and fluorogenicity, a critical parameter in advanced imaging experiments.

Products are for research use only. Not for human use.

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