5, 7, 8-Trimethoxyflavone


Catalog No. Size PriceQuantity
M32943-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

5,7,8-Trimethoxyflavone (Norwogonin 5,7,8-trimethyl ether), isolated from Andrographis echioides, inhibits NO with an IC50 of 39.1 μM. 5,7,8-Trimethoxyflavone has anti-inflammatory activity.

Product information

CAS Number: 23050-38-6

Molecular Weight: 312.32

Formula: C18H16O5

Chemical Name: 5,7,8-trimethoxy-2-phenyl-4H-chromen-4-one

Smiles: COC1C=C(OC)C(OC)=C2OC(=CC(=O)C=12)C1C=CC=CC=1

InChiKey: VFRLJCKMHUJGFR-UHFFFAOYSA-N

InChi: InChI=1S/C18H16O5/c1-20-14-10-15(21-2)17(22-3)18-16(14)12(19)9-13(23-18)11-7-5-4-6-8-11/h4-10H,1-3H3

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

5,7,8-Trimethoxyflavone (Norwogonin 5,7,8-trimethyl ether; 8, 16, 32, 64 μM; for 24 hours) decreases NO production in a dose-dependent manner in RAW 264.7 macrophages. 5,7,8-Trimethoxyflavone does not change lipopolysaccharide (LPS)-induced (100 ng/mL) cell viability.

Products are for research use only. Not for human use.

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