Metyrosine


Catalog No. Size PriceQuantity
M32964-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

Metyrosine is a selective tyrosine hydroxylase enzyme inhibitor. Metyrosine exerts anti-inflammatory and anti-ulcerative effects. Metyrosine significantly inhibits high COX-2 activity. Metyrosine is a very effective agent for blood pressure control.

Product information

CAS Number: 672-87-7

Molecular Weight: 195.22

Formula: C10H13NO3

Chemical Name: (2S)-2-amino-3-(4-hydroxyphenyl)-2-methylpropanoic acid

Smiles: C[C@](N)(CC1=CC=C(O)C=C1)C(O)=O

InChiKey: NHTGHBARYWONDQ-JTQLQIEISA-N

InChi: InChI=1S/C10H13NO3/c1-10(11,9(13)14)6-7-2-4-8(12)5-3-7/h2-5,12H,6,11H2,1H3,(H,13,14)/t10-/m0/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: H2O : 5 mg/mL (25.61 mM; ultrasonic and warming and adjust pH to 2 with HCl and heat to 60°C).

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

Metyrosine acts by inhibiting tyrosine hydroxylase, thus causing depletion of adrenal stores of catecholamines.

In Vivo:

Metyrosine (50-200 mg/kg; i.p.) reduces carrageenan inflammation. Metyrosine (50-200 mg/kg; i.p.) shows antiulcerative activity is 87.7%, 93.7% and 95.5% for 50, 100 and 200 mg/kg doses of metyrosine, respectively.

Products are for research use only. Not for human use.

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