CYP17-IN-1


Catalog No. Size PriceQuantity
M32990-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

CYP17-IN-1 (compound 9c) is a potent and orally active CYP17 inhibitor against rat and human CYP17 with IC50s of 15.8 and 20.1 nM.

Product information

CAS Number: 2093317-51-0

Molecular Weight: 312.40

Formula: C18H17FN2S

Chemical Name: 12-fluoro-5-[(4-methylpyridin-3-yl)methyl]-8-thia-5-azatricyclo[7.4.0.0²,⁷]trideca-1(13),2(7),9,11-tetraene

Smiles: CC1=CC=NC=C1CN1CC2SC3=CC=C(F)C=C3C=2CC1

InChiKey: ATNGVPCHSCNOMP-UHFFFAOYSA-N

InChi: InChI=1S/C18H17FN2S/c1-12-4-6-20-9-13(12)10-21-7-5-15-16-8-14(19)2-3-17(16)22-18(15)11-21/h2-4,6,8-9H,5,7,10-11H2,1H3

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

CYP17-IN-1 (compound 9c) exhibits an IC50 value of 8.5 µM against CYP3A4.

In Vivo:

CYP17-IN-1 (compound 9c) reduces plasma testosterone level in a dose-dependent manner in Sprague-Dawley rats.

Products are for research use only. Not for human use.

Payment & Security

PayPal Venmo

Your payment information is processed securely. We do not store credit card details nor have access to your credit card information.

You may also like

Recently viewed