2-Methylquinazolin-4-ol


Catalog No. Size PriceQuantity
M33167-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

2-Methylquinazolin-4-ol is a potent competitive poly(ADP-ribose) synthetase inhibitor, with a Ki of 1.1 μM. 2-Methylquinazolin-4-ol mammalian aspartate transcarbamylase (ATCase) inhibitor, with 0.20 mM.

Product information

CAS Number: 1769-24-0

Molecular Weight: 160.17

Formula: C9H8N2O

Chemical Name: 2-methyl-3,4-dihydroquinazolin-4-one

Smiles: CC1NC(=O)C2=CC=CC=C2N=1

InChiKey: FIEYHAAMDAPVCH-UHFFFAOYSA-N

InChi: InChI=1S/C9H8N2O/c1-6-10-8-5-3-2-4-7(8)9(12)11-6/h2-5H,1H3,(H,10,11,12)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO : 50 mg/mL (312.17 mM; Need ultrasonic). H2O : < 0.1 mg/mL (insoluble).

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

2-Methylquinazolin-4-ol inhibits ATCase in a concentration-dependent manner.

In Vivo:

2-Methylquinazolin-4-ol (0.2-1 mg; i.g.; for two days) inhibits ATCase in a dosedependent manner in vivo.

Products are for research use only. Not for human use.

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