Description
Tween 80 (Polysorbate 80), a surfactant, has been widely used as a solvent for pharmacological experiments. Tween 80 can also reduce bacterial attachment and inhibit biofilm formation.
Product information
CAS Number: 9005-65-6
Molecular Weight: 604.81
Formula: C32H60O10
Chemical Name: 2-{2-[3,4-bis(2-hydroxyethoxy)oxolan-2-yl]-2-(2-hydroxyethoxy)ethoxy}ethyl (9E)-octadec-9-enoate
Smiles: CCCCCCCC/C=C/CCCCCCCC(=O)OCCOCC(OCCO)C1OCC(OCCO)C1OCCO
InChiKey: HDTIFOGXOGLRCB-MDZDMXLPSA-N
InChi: InChI=1S/C32H60O10/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-30(36)40-25-24-37-26-28(38-21-18-33)32-31(41-23-20-35)29(27-42-32)39-22-19-34/h9-10,28-29,31-35H,2-8,11-27H2,1H3/b10-9+
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vitro:
Tween 80 (Polysorbate 80) is a surfactant which can also reduce bacterial attachment and inhibit biofilm formation. Solubility enhancement as high as 100-fold is achieved using 1% Tween 80 in vitro.
In Vivo:
Tween 80 (Polysorbate 80) (IP; 10 ml/kg) significantly decreases locomotor activity at a concentration of 32% in saline (v/v) in male outbred (BALB/c x DBA/Z)F1 mice weighing 24-30 g.
Products are for research use only. Not for human use.
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