Description
Tiliroside, a glycosidic flavonoid, possesses anti-diabetic activities. Tiliroside is a noncompetitive inhibitor of α-amylase with a Ki value of 84.2 μM. Tiliroside inhibits carbohydrate digestion and glucose absorption in the gastrointestinal tract.
Product information
CAS Number: 20316-62-5
Molecular Weight: 594.52
Formula: C30H26O13
Chemical Name: [(2R,3S,4S,5R,6S)-6-{[5,7-dihydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-chromen-3-yl]oxy}-3,4,5-trihydroxyoxan-2-yl]methyl (2E)-3-(4-hydroxyphenyl)prop-2-enoate
Smiles: O[C@@H]1[C@@H](O)[C@@H](O[C@H](COC(=O)/C=C/C2C=CC(O)=CC=2)[C@H]1O)OC1=C(OC2=CC(O)=CC(O)=C2C1=O)C1C=CC(O)=CC=1
InChiKey: DVGGLGXQSFURLP-VWMSDXGPSA-N
InChi: InChI=1S/C30H26O13/c31-16-6-1-14(2-7-16)3-10-22(35)40-13-21-24(36)26(38)27(39)30(42-21)43-29-25(37)23-19(34)11-18(33)12-20(23)41-28(29)15-4-8-17(32)9-5-15/h1-12,21,24,26-27,30-34,36,38-39H,13H2/b10-3+/t21-,24-,26+,27-,30+/m1/s1
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Solubility: DMSO : 250 mg/mL (420.51 mM; Need ultrasonic).
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vitro:
Tiliroside inhibits pancreatic α-amylase (IC50=0.28 mM) in vitro.
In Vivo:
In male ICR mice, the increase in postprandial plasma glucose levels was significantly suppressed in the Tiliroside-administered group.
Products are for research use only. Not for human use.
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