Description
Bermoprofen (AD-1590) is an orally active non-steroidal anti-inflammatory agent. Bermoprofen has potent antipyretic and analgesic activities with a short biological half-life. Bermoprofen is a potent antagonist of LPS-induced fever in rabbits.
Product information
CAS Number: 78499-27-1
Molecular Weight: 296.32
Formula: C18H16O4
Chemical Name: 2-{13-methyl-9-oxo-2-oxatricyclo[9.4.0.0³,⁸]pentadeca-1(15),3,5,7,11,13-hexaen-6-yl}propanoic acid
Smiles: CC1C=C2CC(=O)C3=CC(=CC=C3OC2=CC=1)C(C)C(O)=O
InChiKey: REHLODZXMGOGQP-UHFFFAOYSA-N
InChi: InChI=1S/C18H16O4/c1-10-3-5-16-13(7-10)9-15(19)14-8-12(11(2)18(20)21)4-6-17(14)22-16/h3-8,11H,9H2,1-2H3,(H,20,21)
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vitro:
Bermoprofen (AD-1590) shows ulcerogenic activity as a side-effect like other nonsteroidal anti-inflammatory agents.
In Vivo:
Bermoprofen (AD-1590) (0.04-0.1 mg/kg; p.o.) shows a dose-related antipyretic activity in LPS-induced febrile rabbits.
Products are for research use only. Not for human use.
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