MRN73473

MRN73473, also known as Menin-MLL inhibitor 20, is an irreversible menin-MLL interaction inhibitor with antitumor activities. This compound was first reported in patent WO2020142557A1 (compound 6). This product has no formal name at the moment. For the convenience of communication, a temporal code name was therefore proposed according to MedKoo Chemical Nomenclature (see web page: https://www.medkoo.com/page/naming)

Product information

CAS Number: 2448173-47-3

Molecular Weight: 612.72

Formula: C33H40N8O4

Chemical Name: tert-butyl (R)-(1-((2-((4-(4-morpholino-7H-pyrrolo[2, 3-d]pyrimidin-6-yl)phenyl)carbamoyl)pyridin-4-yl)methyl)piperidin-3-yl)carbamate

Smiles: CC(C)(C)OC(=O)N[C@H]1CN(CC2=CC(=NC=C2)C(=O)NC2C=CC(=CC=2)C2=CC3=C(N=CN=C3N2)N2CCOCC2)CCC1

InChiKey: MPFHTFMFYAODPE-RUZDIDTESA-N

InChi: InChI=1S/C33H40N8O4/c1-33(2,3)45-32(43)38-25-5-4-12-40(20-25)19-22-10-11-34-28(17-22)31(42)37-24-8-6-23(7-9-24)27-18-26-29(39-27)35-21-36-30(26)41-13-15-44-16-14-41/h6-11,17-18,21,25H,4-5,12-16,19-20H2,1-3H3,(H,37,42)(H,38,43)(H,35,36,39)/t25-/m1/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: To be determined

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

Products are for research use only. Not for human use.