MCX 28


Catalog No. Size PriceQuantity
M33511-C Contact sales@xcessbio.com for quotation $100

Description

MCX 28, a triple PI3K/mTOR/PIM inhibitor, displays low nanomolar activity.

Product information

CAS Number: 1414453-58-9

Molecular Weight: 549.64

Formula: C25H19N5O4S3

Chemical Name: 25-methoxy-31-methyl-3, 22, 30-trithia-6, 8, 15, 23, 26-pentaazahexacyclo[22.3.1.1, .1, .1, .0, ]hentriaconta-1(27), 2(31), 4, 6, 8, 10, 12, 17(29), 18, 20, 24(28), 25-dodecaene-16

Smiles: CC1C2=NC=NC3C4=CC=C(CNC(=O)C5=CC(=CC=C5)S(=O)(=O)NC5=CC(=CN=C5OC)C=1SC=32)S4

InChiKey: LPJAKJUVEMSSSX-UHFFFAOYSA-N

InChi: InChI=1S/C25H19N5O4S3/c1-13-20-23-21(29-12-28-20)19-7-6-16(35-19)11-26-24(31)14-4-3-5-17(8-14)37(32,33)30-18-9-15(22(13)36-23)10-27-25(18)34-2/h3-10,12,30H,11H2,1-2H3,(H,26,31)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: To be determined

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

References:

  1. Martínez-González S, et al. Macrocyclization as a Source of Desired Polypharmacology. Discovery of Triple PI3K/mTOR/PIM Inhibitors. ACS Med Chem Lett. 2021 Nov 2;12(11):1794-1801.

Products are for research use only. Not for human use.

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