Description
HIV-1 inhibitor-9 is found to be potent inhibitor against the wild-type (WT) HIV-1 strain or multiple NNRTI-resistant strains at low nanomolar levels.
Product information
CAS Number: 2708201-36-7
Molecular Weight: 395.46
Formula: C24H21N5O
Chemical Name: 4-({2-[(4-cyanophenyl)amino]-5, 6, 7, 8-tetrahydroquinazolin-4-yl}oxy)-3, 5-dimethylbenzonitrile
Smiles: CC1C=C(C=C(C)C=1OC1=NC(NC2C=CC(=CC=2)C#N)=NC2CCCCC=21)C#N
InChiKey: HBZCSFIXNDKLEL-UHFFFAOYSA-N
InChi: InChI=1S/C24H21N5O/c1-15-11-18(14-26)12-16(2)22(15)30-23-20-5-3-4-6-21(20)28-24(29-23)27-19-9-7-17(13-25)8-10-19/h7-12H,3-6H2,1-2H3,(H,27,28,29)
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Solubility: To be determined
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
References:
- Huang B, et al. Structure-Based Design and Discovery of Pyridyl-Bearing Fused Bicyclic HIV-1 Inhibitors: Synthesis, Biological Characterization, and Molecular Modeling Studies. J Med Chem. 2021 Sep 23;64(18):13604-13621.
Products are for research use only. Not for human use.
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