Description
Antileishmanial agent-1 exhibits the activity against L. amazonensis promastigotes (IC50 = 15.52 μM) and intracellular amastigotes (IC50 = 4.10 μM).
Product information
CAS Number: 2454115-43-4
Molecular Weight: 409.08
Formula: C15H11Br2N3O
Chemical Name: (4-bromophenyl)[1-(4-bromophenyl)-1H-1, 2, 3-triazol-4-yl]methanol
Smiles: OC(C1=CN(N=N1)C1C=CC(Br)=CC=1)C1C=CC(Br)=CC=1
InChiKey: ADBZXYOFJKVXLD-UHFFFAOYSA-N
InChi: InChI=1S/C15H11Br2N3O/c16-11-3-1-10(2-4-11)15(21)14-9-20(19-18-14)13-7-5-12(17)6-8-13/h1-9,15,21H
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Solubility: To be determined
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
References:
- Almeida-Souza F, et al. Nitric Oxide Induction in Peritoneal Macrophages by a 1,2,3-Triazole Derivative Improves Its Efficacy upon Leishmania amazonensisIn Vitro Infection. J Med Chem. 2021 Sep 9;64(17):12691-12704.
Products are for research use only. Not for human use.
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