TCMDC-125457


Catalog No. Size PriceQuantity
M33552-C Contact sales@xcessbio.com for quotation $100

Description

TCMDC-125457 is potent in inducing calcium redistribution but minimally inhibits heme crystallization. TCMDC-125457 demonstrated high efficacy when pulsed in a single-dose combination with artesunate against tightly synchronized artemisinin-resistant ring-stage parasites.

Product information

CAS Number: 872113-12-7

Molecular Weight: 399.83

Formula: C19H18ClN5O3

Chemical Name: N-(5-chloro-2-methoxyphenyl)-2-[N-methyl-1-(2-phenyl-2H-1, 2, 3-triazol-4-yl)formamido]acetamide

Smiles: CN(CC(=O)NC1=CC(Cl)=CC=C1OC)C(=O)C1C=NN(N=1)C1C=CC=CC=1

InChiKey: RHRZUZMCICRKJA-UHFFFAOYSA-N

InChi: InChI=1S/C19H18ClN5O3/c1-24(12-18(26)22-15-10-13(20)8-9-17(15)28-2)19(27)16-11-21-25(23-16)14-6-4-3-5-7-14/h3-11H,12H2,1-2H3,(H,22,26)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: To be determined

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

References:

  1. Chia W, et al. High-Content Phenotypic Screen of a Focused TCAMS Drug Library Identifies Novel Disruptors of the Malaria Parasite Calcium Dynamics. ACS Chem Biol. 2021 Nov 19;16(11):2348-2372.

Products are for research use only. Not for human use.

Payment & Security

PayPal Venmo

Your payment information is processed securely. We do not store credit card details nor have access to your credit card information.

Estimate shipping

You may also like

Recently viewed